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Services Offered

  • Comprehensive literature search

  • Step-wise screening to select relevant articles

  • Two screeners for all levels of screening and verification

  • Independent unbiased review of the literature

  • Statistical analysis

  • GRADE®


Cochrane Collaboration

The Cochrane Collaboration Handbook of Systematic Reviews and Interventions states,  Publication of a protocol for a review prior to knowledge of the available studies reduces the impact of review authors’ biases, promotes transparency of methods and processesLearn more

Literature Search


Using the review questions; key concepts and inclusion/exclusion criteria, a librarian builds a complex and comprehensive literature search. Working with a librarian specifically trained in systematic reviews searches ensures the right body of evidence is available for screening.

Literature Reveiw


  • Title and abstract, full-text screening and critical appraisal screening
  • Duplicate screening at all levels
  • Screening questions tailored to reflect your research question
  • Iterative process

Data Extraction

Collected & Verified

Data are collected and verified by two researchers for all included studies. Study methodology and characteristics. Data are reported for outcomes of interest and the subgroup data.

Critical Appraisal

Critical Appraisal Tools

Assessing the quality of all studies that meet the inclusion criteria using critical appraisal tools suitable for type of review.

Go to merst.ca/tools


Data Synthesis Process

The body of evidence informs the best method for synthesis which can include meta-analysis or narrative/thematic summary.

Learn more…



The GRADE working group

The Grading of Recommendations, Development and Evaluation (GRADE) assesses the certainty of the evidence and is a key component in the development of recommendation and guidelines. Read more at the gradeworking group website